ABSTRACT
With the popularization and application of antiseptic drugs, the abuse of antiseptic drugs and various un reasonable applications have also become a serious medical problem. The prescriptions of antibiotics in or hospital were randomly selected for statistical analysis. Further, we analyzed the vaious situations of the use of antibiotics in outpatient department, and calculated the DDDs of different drugs based on the defined daily dose [DDD]. The results showed that there were 403 unreasonable prescriptions, accounting for 24.9% of the drug prescriptions. The main problem of irrational prescriptions were unsuitable drugs, non indications and improper frequency of adminstration, which accounted for 27.1%, 21.3% and 18.3%. It is suggested that the quality department of the hospital should strengthen the special training for rational use of antimicrobial agents, intervene in time and effectively, and gradually change post evaluation into prevention intervention in advance